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Materials Used in Perfumery 70% - 100% Aroma Chemicals
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The following information, based on Aroma Chemicals listed in the right-hand column (70% - 100% Aroma Chemicals) of Materials Used in Perfumery, is linked to source sites.
For your conveninence, two sources of MSDS (Material Safety Data Sheets) are given here.
http://www.sigma-aldrich.com/saws.nsf/Home?OpenFrameset
Cornell
Interpreting an MSDS
Other MSDS links available from EHN's page M
From Cornell: http://MSDS.PDC.CORNELL.EDU/msds/siri/msds/h/q248/q398.html Health Hazard Data ====== LD50-LC50 Mixture: LD50 (ORAL,RAT)=930 MG/KG Route Of Entry - Inhalation: YES Route Of Entry - Skin: YES Route Of Entry - Ingestion: NO Health Haz Acute And Chronic:
ACUTE:HARMFUL IF SWALLOWED, INHALED, ABSORBED THRU SKIN. CHRONIC: CARCINOGEN. MAY ALTER GENETIC MATERIAL. BLOOD EFFECTS. Carcinogenicity - NTP: YES Carcinogenicity - IARC: YES Carcinogenicity - OSHA: YES
Explanation Carcinogenicity: CONTAINS Benzene [71-43-2] WHICH IS LISTED BY
Signs/Symptoms Of Overexp: NAUSEA, DIZZ,HEAD, NARCOTIC EFFECT. CANCER.
Med Cond Aggravated By Exp: NONE SPECIFIED BY MANUFACTURER. Label Required: YES
GALAXOLIDE
Section V : HEALTH HAZARD DATA
"INHALATION: NO" and yet it is a frgrance chemical! Who is kidding whom?
CARCINOGENICITY : OSHA : No IARC : No MEDICAL CONDITIONS AGGRAVATED BY OVEREXPOSURE : None known. EFFECTS OF OVEREXPOSURE : May be irritating to skin and eyes. EYE CONTACT EFFECTS : May be irritating to eyes. SKIN CONTACT EFFECTS : May be irritating to skin. INHALATION EFFECTS : May be irritating if inhaled. INGESTION EFFECTS : May be harmful if swallowed.
NOTE :
SKIN CONTACT : Remove any contaminated clothing or shoes. Wash affected areas
INHALATION : Remove from the exposure to fresh air. If breathing has stopped,
INGESTION : Give water to dilute. Contact a physician or local
Toluene: Benzyl Acetate
From Cornell: http://MSDS.PDC.CORNELL.EDU/msds/siri/msds/h/q225/q108.html Health Hazard Data ==== LD50-LC50 Mixture: LD50:(ORAL RAT)636 MG/KG. Route Of Entry - Inhalation: YES Route Of Entry - Skin: YES Route Of Entry - Ingestion: YES Health Haz Acute And Chronic: ACUTE:HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES SEVERE IRRITATION. HIGH CONCENTRATIONS ARE EXTREMELY DESTRUCTIVE TO TISSUES OF THE MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT, EYES, AND SKIN. SYMPTOMS OF EXPOSURE MAY INCLUDE BURNING SENSATION, COUGHING, WHEEZING, LARYNGITIS, (EFTS OF OVEREXP) Carcinogenicity - NTP: NO Carcinogenicity - IARC: NO Carcinogenicity - OSHA: NO Explanation Carcinogenicity: NOT RELEVANT.
Signs/Symptoms Of Overexp: HLTH HAZ:SHORTNESS OF BREATH, HEADACHE,
CHRONIC:MAY CAUSE NERVOUS SYSTEM DISTURBANCES. INHALATION STUDIES Med Cond Aggravated By Exp: NONE SPECIFIED BY MANUFACTURER. Emergency/First Aid Proc:
EYE:IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
SKIN:IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER WHILE
INHAL:MOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIFICIAL RESPIRATION. INGEST:WASH OUT MOUTH WITH WATER PROVIDED PERS IS CONSCIOUS. CALL MD. Label Required: YES
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Benzyl acetate
Inhalation: Inhalation of concentrated vapor will irritate throat and lungs. Prolonged inhalation of vapors may cause serious health effects including shortness of breath, loss of coordination, and loss of consciousness. Breathing high concentrations of vapor may also cause anesthetic effects. Eye Contact: Vapor is irritating to the eyes.
Skin Contact: May cause skin irritation. A case of dermatitis as been recorded, although
Ingestion: General intestinal irritation, vomiting, and diarrhea are reported to result from --------
CHRONIC HEALTH HAZARDS:
Ingestion: The NTP study of benzyl acetate reported that "Nasal lesions associated with
No other CHRONIC HEALTH hazard information is available.
from Mangalam Enterprises http://www.mangalamchem.com/1-acytNapth.html
Formula
Mol. Wt.
Water Quality - TMDL Fact Sheet
" What is a Total Maximum Daily Load (TMDL) and why should I care? How can a TMDL
"The pollutants of concern vary from watershed to watershed. In much of rural Idaho,
From Aldrich: http://www.sigma-aldrich.com/
CAS #: 134-20-3 - - - - - - - -TOXICOLOGICAL INFORMATION - - - - - - - - ACUTE EFFECTS CAUSES SKIN IRRITATION. MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION.
VAPOR OR MIST IS IRRITATING TO THE EYES, MUCOUS MEMBRANES AND
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
CHRONIC EFFECTS
Turpentine
Pinene (Linalool)
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**See:
The materials used in perfumery
"PERFUME CONCENTRATE ('COMPOUND')
is typically a liquid compound made up from a mixture of
aroma materials of synthetic and natural origin
from the following groups: ..."
Note from barb: Please check the columns under, "Aroma Chemicals 70-100%"
http://www.perfumersworld.com/chems/material.htm
Health Canada
http://www.hc-sc.gc.ca/
Note: Health Canada was not a part of this press conference, but I've included them here so you can see the regulations regarding cosmetics in Canada. -- barb
R.S., c. F-27, s. 15.
Cosmetics
Prohibited sales of cosmetics
16. No person shall sell any cosmetic that
(a) has in or on it any substance that may cause injury to the health of the user when the cosmetic is used,
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(i) according to the directions on the label or accompanying the cosmetic, or
(ii) for such purposes and by such methods of use as are customary or usual therefor;
(b) consists in whole or in part of any filthy or decomposed substance or of any foreign matter; or
(c) was manufactured, prepared, preserved, packaged or stored under unsanitary conditions.
Where standard prescribed for cosmetic
17. Where a standard has been prescribed for a cosmetic, no person shall label, package, sell or advertise any article in such a manner that it is likely to be mistaken for that cosmetic, unless the article complies with the prescribed standard.
http://canada2.justice.gc.ca/ftp/en/Laws/Chap/F/F-27.txt
US Food and Drug Administration - Cosmetics
Note: US FDA was not a part of this press conference, but I've included them
here so you can see the regulations regarding cosmetics in the USA. -- barb
To get to US Codes: From http://uscode.house.gov/usc.htm enter "21" in "Title" box and "361" in 'Section" box, click Search. Click on the document that appears in their next screen. When finished with the US Codes, just click the close box to return to this page. -- barb
[Title 21] Sec. 361. Adulterated cosmetics
-STATUTE-
A cosmetic shall be deemed to be adulterated -
(a) If it bears or contains any poisonous or deleterious!
substance which may render it injurious to users under the
conditions of use prescribed in the labeling thereof, or under such
conditions of use as are customary or usual, except that this
provision shall not apply to coal-tar hair dye, ...
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!Query from barb: Folks, just what is it I'm missing here?
From American Heritage Dictionary --
POISONOUS: " Having the capability of harming or killing by or as if by poison; toxic or venomous."
DELETERIOUS: "Having a harmful effect; injurious."
[Title 21] Sec. 362. Misbranded cosmetics
-STATUTE-
A cosmetic shall be deemed to be misbranded -
(a) If its labeling is false or misleading in any particular.
(b) If in package form unless it bears a label containing (1) the
name and place of business of the manufacturer, packer, or
distributor; and (2) an accurate statement of the quantity of the
contents in terms of weight, measure, or numerical count: Provided,
That under clause (2) of this paragraph reasonable variations shall
be permitted, and exemptions as to small packages shall be
established, by regulations prescribed by the Secretary.
(c) If any word, statement, or other information required by or
under authority of this chapter to appear on the label or labeling
is not prominently placed thereon with such conspicuousness (as
compared with other words, statements, designs, or devices, in the
labeling) and in such terms as to render it likely to be read and
understood by the ordinary individual under customary conditions of
purchase and use. ...
21 CFR 740.10 COSMETIC PRODUCT WARNING STATEMENTS
[See FDA's PART 740 -- Cosmetic Product Warning Statements at http://vm.cfsan.fda.gov/~lrd/cfr740.html]
Note: This link will open a new page; when finished reading, just click the close box to return to this page. Also, once into the FDA page, scroll to "740.10 " or use your find command. -- barb
Subpart B--Warning Statements
Sec. 740.10 Labeling of cosmetic products for which adequate
substantiation of safety has not been obtained.
(a) Each ingredient used in a cosmetic product and each finished cosmetic product shall be adequately substantiated for safety prior to marketing. Any such ingredient or product whose safety is not adequately substantiated prior to marketing is misbranded unless it contains the following conspicuous statement on the principal display panel:
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Warning--The safety of this product has not been determined.
For more information on the safety of fragrances, please visit EHN's Citizens' Petition before the US FDA at http://www.ehnca.org/www/FDApetition/bkgrinfo.htm
Return to EHN's General Links, page A, articles on Halifax
http://www.ehnca.org/www/ehnlinx/a.htm#Halifaxs
Another Perspective: Halifax Press Releases and Statements
http://www.ehnca.org/www/ehnlinx/aaprbb.htm
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EHN's homepage www.ehnca.org
perfume, fragrances -- The Environmental Health Network (EHN) [of California] is a 501 (c) (3) non profit agency and offers support and information for the chemically injured. Learn about the toxicity of fragrances from the work of Julia Kendall and Betty Bridges, RN, get The BEST of the Reactor, join EHN and receive The New Reactor. See what influence the Chemical Manufacturers have had against those of us with EI. The URL for this page is http://www.ehnca.org